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500ug
| 产品编号 | bs-13496P |
| 英文名称 | GPAA1 Antibody Blocking Peptide |
| 中文名称 | 糖基磷脂酰肌醇锚连接蛋白1封闭多肽 |
| 英文别名 | Anchor attachment protein 1 (Gaa1p, yeast) homolog; GAA1; GAA1; GAA1; GAA1 protein homolog; Glycophosphatidylinositol anchor attachment 1; Glycosylphosphatidylinositol anchor attachment 1 protein; Glycosylphosphatidylinositol anchor attachment 1 protein; Glycosylphosphatidylinositol anchor attachment 1 protein; Glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast); GPAA 1; GPAA1; GPAA1_HUMAN; GPAA1P anchor attachment protein 1 homolog; GPI anchor attachment protein 1; GPI anchor attachment protein 1; GPI anchor attachment protein 1; GPI transamidase subunit; hGAA1. |
| 纯化方法 | HPLC |
| 亚基 | Forms a complex with PIGK/GPI8, PIGT, PIGU and PIGS. |
| 亚细胞定位 | Endoplasmic reticulum membrane. |
| 组织特异性 | Ubiquitously expressed in fetal and adult tissues. Expressed at higher levels in fetal tissues than adult tissues. |
| 功能 | Essential for GPI-anchoring of precursor proteins but not for GPI synthesis. Acts before or during formation of the carbonyl intermediate. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Glycosylphosphatidylinositol (GPI) acts as a membrane anchor for cell surface proteins. Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1), also designated GPI anchor attachment protein 1 or GAA1 protein homolog, is a membrane protein localized to the endoplasmic reticulum which is involved in GPI-anchor biosynthesis. GPAA1 is crucial for GPI-anchoring of precursor proteins and catalyzes the attachment of GPI to proteins containing a C-terminal GPR attachment signal. GAA1 contains an N-terminal signal sequence, one cAMP- and cGMP-dependent protein kinase phosphorylation site, two potential N-glycosylation sites, one leucine zipper pattern and eight putative transmembrane domains. GPAA1 is ubiquitously expressed and shows higher levels of expression in fetal tissues than in adult tissues. |
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GPAA1 Antibody Blocking Peptide(bs-13496P)-500ug
¥880







