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- bs-17615P
- 2025年10月16日
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500ug
| 产品编号 | bs-17615P |
| 英文名称 | SPACA3 Antibody Blocking Peptide |
| 中文名称 | 精子顶体膜相关蛋白3封闭多肽 |
| 英文别名 | 1700025M08Rik; ALLP17; Cancer/testis antigen 54; sperm acrosome associated 3; CT54; LYC3; Lysozyme like sperm specific secretory protein ALLP17; Lysozyme-like acrosomal sperm-specific secretory protein ALLP-17; Lysozyme-like protein 3; LYZL3; processed form; SACA3_HUMAN; SLLP1; SPACA3; Sperm acrosome associated 3; Sperm acrosome membrane-associated protein 3; Sperm lysozyme-like protein 1; Sperm protein reactive with antisperm antibodies; Sperm protein reactive with ASA; 1. |
| 纯化方法 | HPLC |
| 研究领域 | Developmental Biology > Reproduction > Fertilisation Immunology > Innate Immunity > Macrophage / Inflamm. Signal Transduction > Protein Trafficking > Organelle Proteins |
| 亚细胞定位 | Secreted and Cytoplasmic vesicle > secretory vesicle > acrosome membrane. Anterior acrosome in non-capacitated spermatozoa and retained in the equatorial segment and in the luminal face of both the inner and outer acrosomal membranes following capacitation and the acrosome reaction. |
| 组织特异性 | The processed form is expressed in sperm (at protein level). Expressed in testis, epididymis and placenta. |
| 翻译后修饰 | The processed form derives from the membrane form by proteolytic processing. |
| 相似性 | Belongs to the glycosyl hydrolase 22 family. |
| 功能 | Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | SPACA3 is a 215 amino acid protein that participates in the fusion and adhesion of sperm and egg plasma membrane during fertilization. Identified as a novel cancer/testis antigen in hematologic malignancies, SPACA3 has the ability to elicit B-cell immune responses in patients with cancer and is considered a potential target for immunotherapy. A member of the glycosyl hydrolase 22 family which is expressed in testis, placenta and epididymis, SPACA3 exists as two alternatively spliced isoforms; SPACA3 isoform 1 is a single-pass type II membrane protein of the sperm acrosome whereas SPACA3 isoform 2 is a secreted protein. |
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SPACA3 Antibody Blocking Peptide(bs-17615P)-500ug
￥880
