Human Cadherin 16 Ready-To-Use IHC Kit(IHC0577H)-50T

Human Cadherin 16 Ready-To-Use

IHC Kit(IHC0577H)-50T
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  • IHC0577H
  • 2025年10月15日
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      50T

    产品编号 IHC0577H
    英文名称 Human Cadherin 16 Ready-To-Use IHC Kit
    中文名称 人钙粘蛋白16即用型免疫组化试剂盒
    英文别名 CDH16; UNQ695/PRO1340
    产品应用 IHC-P

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应 Human
    亚细胞定位 #Cell membrane #Membrane
    组织特异性 Kidney specific.
    功能 Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
    保存条件 Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.
    背景资料 The cadherins are a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. Cadherin-16, also known as Ksp-Cadherin, is a type I membrane protein which is kidney-specific. Cadherin-16 is expressed exclusively in the basolateral membrane of renal tubular epithelial cells. The human Ksp-cadherin gene (Cadherin-16) maps to chromosome 16q21-proximal 16q22. The mouse Ksp-cadherin gene was localized to a highly syntenic region of distal Chromosome 8.

     

    应用 推荐稀释比例

     

    Immunohistochemical analysis of paraffin embedded Human kidney tissue slide using IHC0577H (Human Cadherin 16 Kit).

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