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- IHC0332H
- 2025年10月15日
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50T
| 产品编号 | IHC0332H |
| 英文名称 | Human Cystatin-C Ready-To-Use IHC Kit |
| 中文名称 | 人胱抑素C/半胱氨酸蛋白酶抑制剂C即用型免疫组化试剂盒 |
| 英文别名 | ARMD11; CST3; CysC; HEL-S-2; AD8; Cst3; Cystatin 3; Cystatin C |
| 产品应用 | IHC-P Not yet tested in other applications. |
| 交叉反应 | Human |
| 亚基 | Homodimer. |
| 亚细胞定位 | #Amyloid #Secreted |
| 组织特异性 | Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in various body fluids, such as the cerebrospinal fluid and plasma. Expressed in highest levels in the epididymis, vas deferens, brain, thymus, and ovary and the lowest in the submandibular gland. |
| 翻译后修饰 | The Thr-25 variant is O-glycosylated with a core 1 or possibly core 8 glycan. The signal peptide of the O-glycosylated Thr-25 variant is cleaved between Ala-20 and Val-21. |
| 相似性 | Belongs to the cystatin family. |
| 功能 | As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity. |
| 保存条件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 背景资料 | Cystatin C, a member of the type 2 cystatin superfamily, is a potent inhibitor of cysteine proteinases, both endogenous (lysosomal cathepsins), and pathogenic. Cystatin C is a 13 kDa secreted protein which is found in high concentrations in biological fluids and is thought to be expressed by all human nucleated cells. Changes in Cystatin C have been documented in a number of cardiovascular diseases, including atherosclerosis, amyloid angiopathy and myocardial infarction. Its low molecular weight also means that Cystatin C can be used as a marker of renal failure. |
| 应用 | 推荐稀释比例 |
Immunohistochemical analysis of paraffin embedded human kidney tissue slide using IHC0332H (Human Cystatin-C Kit).
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Human Cystatin-C Ready-To-Use IHC Kit(IHC0332H)-50T
￥3200
