Human Napsin A Ready-To-Use IHC Kit(IHC0287H)-50T

Human Napsin A Ready-To-Use IH

C Kit(IHC0287H)-50T
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  • IHC0287H
  • 2025年10月15日
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      50T

    产品编号 IHC0287H
    英文名称 Human Napsin A Ready-To-Use IHC Kit
    中文名称 人天冬氨酸蛋白酶ASP4即用型免疫组化试剂盒
    英文别名 KAP; Kdap; NAP1; NAPA; NAPSA; SNAPA; napsin-A; Napsin A
    产品应用 IHC-P

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应 Human
    亚细胞定位 Secreted
    组织特异性 Expressed at the highest levels in the kidney, at a moderate level in the lung, and at low levels in the spleen and adipose tissue.
    相似性 Belongs to the peptidase A1 family.
    功能 May be involved in processing of pneumocyte surfactant precursors.
    保存条件 Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.
    注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料 Napsin 1 is an aspartic protease that is generally expressed in the lung, but also present in kidney and in metastatic carcinomas throughout the body. Napsin 1 processes surfactant protein B in healthy pulmonary and renal tissues, but is abnormally regulated when carcinogenesis occurs. Thus, many researchers have found napsin evaluation to be useful in identifying several cancers, and differentiating primary tumors from metastases. When combined with thyroid transcription factor analysis, napsin can be used as a specific biomarker for differentiation of carcinoma types. Napsin has also been associated with pulmonary alveolar proteinosis as well as in protein catabolism in renal tubules.

     

    应用 推荐稀释比例

     

    Immunohistochemical analysis of paraffin embedded human lung tissue slide using IHC0287H (Human Napsin A IHC Kit).
    Immunohistochemical analysis of paraffin embedded human lung cancer tissue slide using IHC0287H (Human Napsin A IHC Kit).

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