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- IHC0129H
- 2025年10月15日
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- 详细信息
- 技术资料
- 规格：
50T
| 产品编号 | IHC0129H |
| 英文名称 | Human NF-L Ready-To-Use IHC Kit |
| 中文名称 | 人低分子量神经丝蛋白即用型免疫组化试剂盒 |
| 产品应用 | IHC-P Not yet tested in other applications. |
| 交叉反应 | Human |
| 性状 | Liquid |
| 研究领域 |
Developmental Biology > Lineage specification > Ectoderm Neuroscience > Cell Adhesion Proteins > Cytoskeletal Proteins > Intermediate Filaments Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Intermediate Filaments > Class IV > Neurofilaments Stem Cells > Lineage Markers > Ectoderm |
| 亚基 | Interacts with ARHGEF28. Interacts with TRIM2. |
| 翻译后修饰 | O-glycosylated. Phosphorylated in the head and rod regions by the PKC kinase PKN1, leading to the inhibition of polymerization. Ubiquitinated in the presence of TRIM2 and UBE2D1. |
| 相似性 | Belongs to the intermediate filament family. |
| 功能 | Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Involved in the maintenance of neuronal caliber, neurofilaments are the intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. NF-L is the light or low molecular weight microfilament subunit and runs on SDS-PAGE gels at approximately 70 kDa. Neurofilament are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. NF-H is the heavy or high molecular weight microfilament subunit and runs on SDS-PAGE gels in the range 180-220 kDa, with some variation in different species. |
| 应用 | 推荐稀释比例 |
Immunohistochemical analysis of paraffin embedded human brain tissue slide using IHC0129H (Human NF-L IHC Kit).
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Human NF-L Ready-To-Use IHC Kit(IHC0129H)-50T
￥3200
