- ￥630 - 1000
- Bioss
- D60667
- 2025年10月17日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 规格：
5mg/10mg
| 规格： | 5mg | 产品价格： | ￥630.0 |
|---|---|---|---|
| 规格： | 10mg | 产品价格： | ￥1000.0 |
| 产品编号 | D60667 |
| 英文名称 | PF-5274857 |
| 英文别名 | PF-5274857 freebase; PF 5274857; PF5274857 |
| 理论分子量 | 436.96 |
| 保存条件 | -20℃ |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | PF-5274857 (PF-5274857 free base) is an effective and selective hedgehog signaling pathway inhibitor (IC50: 5.8 nM and a Ki: 4.6 nM). PF-5274857 is a potentially attractive clinical candidate for the treatment of tumor types including brain tumors and brain metastasis driven by an activated Hh pathway.PF-5274857 was found to effectively penetrate the blood-brain barrier and inhibit Smo activity in the brain of primary medulloblastoma mice, resulting in improved animal survival rates. PF-5274857 was orally available and metabolically stable in vivo. |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
PF-5274857(D60667)-5mg/10mg
￥630 - 1000
