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- 技术资料
- 规格:
1mg/5mg
| 规格: | 1mg | 产品价格: | ¥400.0 |
|---|---|---|---|
| 规格: | 5mg | 产品价格: | ¥1000.0 |
| 产品编号 | D60095 |
| 英文名称 | MCC950 |
| 理论分子量 | 404.4799 |
| 保存条件 | -20℃ |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | CP-456773 (MCC950 (CP-456773) and CRID3) is an effective and specific cytokine release inhibitor and NLRP3 inflammasome inhibitor. CP-456773 inhibits IL-1β secretion and caspase 1 processing. MCC950 blocked canonical and noncanonical NLRP3 activation at nanomolar concentrations. MCC950 specifically inhibited activation of NLRP3 but not the AIM2, NLRC4 or NLRP1 inflammasomes. MCC950 reduced IL-1β production in vivo and attenuated the severity of experimental autoimmune encephalomyelitis (EAE), a disease model of multiple sclerosis. |
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MCC950(D60095)-1mg/5mg
¥400 - 1000






