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1mg/5mg
| 规格: | 1mg | 产品价格: | ¥7700.0 |
|---|---|---|---|
| 规格: | 5mg | 产品价格: | ¥19800.0 |
| 产品编号 | D59445 |
| 英文名称 | ACAT-IN-1 cis isomer |
| 中文名称 | ACAT抑制剂1(顺式异构体) |
| 理论分子量 | 419.51 |
| 保存条件 | Powder: -20℃ for 3 years | In solvent: -80℃ for 1 year |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | ACAT-IN-1 cis isomer is a potent ACAT inhibitor (IC50: 100 nM) for the study of immune system-related diseases. |
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文献和实验The 1,5-Disubstituted Tetrazole Ring as a cis-Amide Bond Surrogate
-methyl amino acid-containing peptides. In the case of angiotensin and thyroliberin (TRH) analogs, the quantity of cis -isomer in aqueous solution was correlated (2 ) with the biological activity. This suggested that the cis -isomer might be the one bound
Enzymatic Production of D-Amino Acids
to obtain either D- or L-amino acids from D,L-mono-substituted hydantoin derivatives. The initial enzymatic reaction step of D,L-mono-substituted hydantoin hydrolysis is catalyzed by a D-hydantoinase after the subsequent racemization of L-isomer to D-isomer
, D.L., and McCloskey, J.A. 1975. Structure of the modified nucleoside Q isolated from Escherichia coli transfer ribonucleic acid. 7‐(4,5‐cis‐Dihydroxy‐1‐cyclopenten‐3‐ylaminomethyl)‐7‐deazaguanosine. Biochemistry 14:4198‐4208
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