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1mg/5mg
| 规格: | 1mg | 产品价格: | ¥1199.0 |
|---|---|---|---|
| 规格: | 5mg | 产品价格: | ¥3111.0 |
| 产品编号 | D56832 |
| 英文名称 | Heme Oxygenase-1-IN-1 |
| 英文别名 | HO-1-IN-1; Heme Oxygenase-1-IN-1 |
| 理论分子量 | 279.18 |
| 保存条件 | Powder: -20℃ for 3 years | In solvent: -80℃ for 1 year |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | HO-1-IN-1 is a heme oxygenase 1 (HO-1) inhibitor (IC50: 250 nM). |
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文献和实验Immunoregulatory Properties of Heme Oxygenase-1
Heme oxygenase-1 (HO-1) is one of the three isoforms of the heme oxygenase enzyme that catabolyzes the degradation of heme into biliverdin with the production of free iron and CO. HO-1 is induced by its substrate and by other stimuli
Heme Oxygenase Activity Current Methods and Applications
The heme oxygenase enzymes (HO-1 and HO-2) oxidize heme to biliver-din-IXα (BVIXα), releasing carbon monoxide (CO) and iron (Fig. 1 ). HO enzymes control the rate of heme degradation and, consequently, also control the redistribution
亦称为色氨酸-2,3-加双氧酶,色氨酸吡咯酶,色氨酸氧化酶,色氨酸过氧化酶。是催化L-色氨酸的吲哚核发生开裂形成甲酰犬尿氨酸反应的酶。EC.1.13.11.11。广泛分布于生物体中。动物存在于肝脏里,以高铁血红素为辅酶,能为像维生素C那种还原剂所活化。如果有底物色氨酸存在,高铁血红素结合能力增强,酶趋向于稳定。因此,当给动物色氨酸时就能延长此酶在体内的半衰期,从而增加酶量。此外,副肾皮质激素也能使酶合成增加。恶性肝癌和胎儿肝脏中不含此酶。在兔肠道里,还含有作用于D-色氨酸形成D-甲酰
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