- ￥657 - 1551
- Bioss
- D55649
- 2025年10月17日
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- 详细信息
- 技术资料
- 规格：
1mg/5mg
| 规格： | 1mg | 产品价格： | ￥657.0 |
|---|---|---|---|
| 规格： | 5mg | 产品价格： | ￥1551.0 |
| 产品编号 | D55649 |
| 英文名称 | AOH1996 |
| 理论分子量 | 426.46 |
| 保存条件 | Powder: -20℃ for 3 years | In solvent: -80℃ for 1 year |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | AOH1996 is an orally active ligand for the replicasome component PCNA (proliferating cell nuclear antigen), targeting the transcription-replication conflict (TRC).AOH1996 interferes with the interaction of PCNA with its binding proteins, leading to DNA replication stress and apoptosis.AOH1996 causes proteasome-dependent rpb1 degradation and lethal DNA damage by stabilizing the interaction between PCNA and RNA polymerase II.AOH1996 acts synergistically with DNA damaging agents to inhibit tumor cell growth. AOH1996 inhibits tumor cell growth by stabilizing the interaction between PCNA and RNA polymerase II, leading to proteasome-dependent rpb1 degradation and lethal DNA damage.AOH1996 acts synergistically with DNA damaging agents. |
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AOH1996(D55649)-1mg/5mg
￥657 - 1551
