- ￥358 - 908
- Bioss
- D54846
- 2025年10月17日
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1mg/5mg
| 规格： | 1mg | 产品价格： | ￥358.0 |
|---|---|---|---|
| 规格： | 5mg | 产品价格： | ￥908.0 |
| 产品编号 | D54846 |
| 英文名称 | KCNQ2/3 activator-1 |
| 英文别名 | N-[4-(6-Fluoro-3; 4-dihydro-2(1H)-isoquinolinyl)-2; 6-dimethylphenyl]-3; 3-dimethylbutanamide |
| 理论分子量 | 368.49 |
| 保存条件 | Powder: -20℃ for 3 years | In solvent: -80℃ for 1 year |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | KCNQ2/3 activator-1 is a Kv7.2/Kv7.3 (KCNQ2/3) potassium channel activator, details from Compound A of patent WO2021113757A1. |
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文献和实验., Miller, J.C., Zeitler, B., Cherone, J.M., Meng, X., Hinkley, S.J., Rebar, E.J., Gregory, P.D., Urnov, F.D., and Jaenisch, R. 2011. Genetic engineering of human pluripotent cells using TALE nucleases. Nat. Biotechnol. 29:731‐734
Determination of Phospholipase C-or Phospholipase D-Catalyzed Phosphatidylcholine Hydrolysis
Signal-activated phospholipase-catalyzed hydrolysis of phosphatidylcholin involves three distinct enzymes: phospholipase A2 , phospholipase C (PLC), and phospholipase D (PLD) (1 ). PLC-catalyzed hydrolysis generates sn -1,2-diacylglycerol
the authors to conclude that AP-1 is likely to be an essential activator of BIC gene transcription, at least during the inflammatory response. Consistent with this conclusion, Baltimore and colleagues noted that several AP-1 binding sites are present
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