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- 规格:
2mg/10mg
| 规格: | 2mg | 产品价格: | ¥580.0 |
|---|---|---|---|
| 规格: | 10mg | 产品价格: | ¥1880.0 |
| 产品编号 | D51160 |
| 英文名称 | PBTZ-169 |
| 中文别名 | DprE1抑制剂 |
| 性状 | Lyophilized |
| 理论分子量 | 456.48 |
| 保存条件 | Store in dry, dark place for one year. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | PBTZ-169, also known as macozinone, is a new drug candidate that inhibits decaprenyl-phosphoribose-epimerase (DprE1), an essential enzyme involved in the cell wall biosynthesis of Corynebacterineae. The MIC values of PBTZ-169 ranged from 0.03 μg/mL to 0.0037 μg/mL. The MIC50 and MIC90 values of PBTZ-169 were 0.0075 and 0.030 μg/mL, respectively. The MIC for PBTZ-169 for N. brasiliensis HUJEG-1 was 0.0037 μg/mL. The MICs of SXT, DA-7218, and BTZ043 for this strain were 9.5/0.5, 8, and 0.125 μg/mL, respectively. |
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PBTZ-169(D51160)-2mg/10mg
¥580 - 1880






