- ￥480 - 1480
- Bioss
- D50975
- 2025年10月17日
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- 详细信息
- 技术资料
- 规格：
2mg/10mg
| 规格： | 2mg | 产品价格： | ￥480.0 |
|---|---|---|---|
| 规格： | 10mg | 产品价格： | ￥1480.0 |
| 产品编号 | D50975 |
| 英文名称 | HLCL-61 |
| 中文别名 | PRMT5抑制剂 |
| 性状 | Lyophilized |
| 理论分子量 | 380.91 |
| 保存条件 | Store in dry, dark place for one year. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | HLCL-61 is a potent and selective Protein arginine methyltransferase-5 (PRMT5) Inhibitor. It shows no inhibitory activity against the type I (PRMT1 and PRMT4) and type II (PRMT7) PRMT family members. HLCL-61 shows effective inhibition of symmetric arginine dimethylation (me2) of histones H3 and H4 in AML samples.Treatment of AML cell lines (MV4-11 and THP-1) and primary blasts with HLCL-61 also results in a decrease of cell viability. HLCL-61 is also effective in promoting apoptosis in MV4-11 and THP-1 cells after 48 h. |
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HLCL-61(D50975)-2mg/10mg
￥480 - 1480
