rHu BRD2 Protein, N-His(bs-103902P)-20ug/50ug/100ug产品图

rHu BRD2 Protein, N-His(bs-103

902P)-20ug/50ug/100ug
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  • ¥980 - 2680
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  • bs-103902P
  • 2026年10月10日
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      20ug/50ug/100ug

    规格:20ug产品价格:¥980.0
    规格:50ug产品价格:¥1880.0
    规格:100ug产品价格:¥2680.0
    产品编号bs-103902P
    英文名称Recombinant Human BRD2 Protein, N-His
    英文别名Really interesting new gene 3 protein; KIAA9001; O27.1.1; BRD2; RING3; Bromodomain-containing protein 2
    性状Lyophilized
    纯化方法AC
    理论分子量15.31 kDa
    储存液Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
    研究领域

    Cell Biology > Proteolysis / Ubiquitin > Proteasome / Ubiquitin > Ubiquitin E3 Enzymes > RING Finger E3 Ligase

    Epigenetics and Nuclear Signaling > Bromodomains

    Epigenetics and Nuclear Signaling > ChIP assays > ChIP antibodies

    Epigenetics and Nuclear Signaling > Transcription > Bromodomain containing

    Epigenetics and Nuclear Signaling > Transcription > Domain Families > Developmental Families

    Signal Transduction > Protein Phosphorylation > Ser / Thr Kinases > Other Kinases

    亚基Homodimer. Interacts with E2F1 and with histone H4acetylated at 'Lys-13'.
    亚细胞定位Nucleus.
    相似性Contains 2 bromo domains.
    _x000D_ Contains 1 ET domain.
    功能May play a role in spermatogenesis or folliculogenesis.
    保存条件Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010]

     

     

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