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- Bioss
- bs-7009P
- 2025年10月15日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-7009P |
| 英文名称 | SART3 Antibody Blocking Peptide |
| 中文名称 | T淋巴细胞识别的鳞状细胞癌SART3封闭多肽 |
| 英文别名 | p110(nrb); SART3; SART-3; Tat interacting protein of 110 kDa; TIP110; SART3_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Tumor biomarkers > Tumor antigens Epigenetics and Nuclear Signaling > Chromatin Binding Proteins > DNA / RNA binding Microbiology > Organism > Virus > RNA Virus > ssRNA positive strand virus > HIV |
| 亚基 | Component of the 7SK snRNP complex at least composed of P-TEFb (composed of CDK9 and CCNT1/cyclin-T1), HEXIM1, HEXIM2, BCDIN3, SART3 proteins and 7SK and U6 snRNAs. Interacts with HIV-1 Tat. Interacts with EIF2C1 and EIF2C2. |
| 亚细胞定位 | Cytoplasm. Nucleus speckle. Note=Localized in speckles. Expressed in the nucleus of all of the malignant tumor cell lines tested and the majority of cancer tissues with various histologies, including squamous cell carcinomas (SCC), adenocarcinomas, melanomas and leukemias cells. However, this protein is undetectable in the nucleus of any cell lines of nonmalignant cells or normal tissues, except for the testis. Expressed in the cytoplasm of all the proliferating cells, including normal and malignant cells, but not in normal tissues, except for the testis and the fetal liver. |
| 组织特异性 | Ubiquitously expressed. |
| 相似性 | Contains 8 HAT repeats. Contains 2 RRM (RNA recognition motif) domains. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | RelevanceSART3 regulates Tat transactivation activity through direct interaction. It may be a cellular factor for HIV1 gene expression and viral replication. |
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bs-7009P
￥880
