CDH12 | N-cadherin 2 Rabbit pAb, Cy5 conj.(bs-13715R-Cy5)-100ul产品图

CDH12 | N-cadherin 2 Rabbit pA

b, Cy5 conj.(bs-13715R-Cy5)-100ul
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  • bs-13715R-Cy5
  • 2026年10月17日
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    • 规格:

      100ul

    产品编号bs-13715R-Cy5
    英文名称CDH12 Rabbit pAb, Cy5 conjugated
    中文名称Cy5标记的脑钙粘蛋白12抗体
    英文别名Br cadherin; BR-cadherin; Brain cadherin; CAD12_HUMAN; cadherin 12(N cadherin 2); Cadherin 12; Cadherin 12 precursor; Cadherin 12 type 2(N cadherin 2); Cadherin 12 type 2; Cadherin neural type 2; Cadherin-12; CDH12; CDHB; FLJ34857; N cadherin 2; N-cadherin 2; Neural type cadherin 2; Neuronal cadherin 2.
    产品应用IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human CDH12
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Cadherins

    亚细胞定位Cell membrane.
    组织特异性Brain.
    相似性Contains 5 cadherin domains.
    功能Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morpho-genesis (1-4). Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity (5,6). The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including catenin b, to regulate cadherin function (7). BR-cadherin (for brain-cadherin, also designated cadherin-12 or N-cadherin 2) is expressed specifically in neurons in the central nervous system and is thought to be involved in neuronal development (8).

     

    应用推荐稀释比例
    {IF}{1:100-500}

     

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