SLU7 Rabbit pAb, AP conj.(bs-8327R-AP)-100ul产品图

SLU7 Rabbit pAb, AP conj.(bs-8

327R-AP)-100ul
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  • bs-8327R-AP
  • 2026年10月17日
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    北京博奥森生物技术有限公司
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    • 规格：

      100ul

    产品编号bs-8327R-AP
    英文名称SLU7 Rabbit pAb, AP conjugated
    中文名称AP标记的SLU7蛋白抗体
    英文别名9G8; hSlu7; MGC9280; Pre mRNA splicing factor SLU7; Pre-mRNA-splicing factor slu7; SLU 7; SLU-7; slu7; SLU7 splicing factor homolog(S. cerevisiae); SLU7 splicing factor homolog; SLU7_HUMAN; Step II splicing factor SLU7; Zinc knuckle motif containing.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human SLU7
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cell Biology > Other Antibodies > Oxidative Stress

    Epigenetics and Nuclear Signaling > DNA / RNA > RNA Processing > Splicing

    Metabolism > Pathways and Processes > Redox metabolism > Oxidative stress

    Signal Transduction > Protein Trafficking > Nuclear Import / Export

    亚基Component of late spliceosomal complexes. Associates with the spliceosome prior to recognition of the 3'-splice site for step II, probably during catalysis of step I.
    亚细胞定位Nucleus. Cytoplasm. Predominantly nuclear. Shuttling between the nucleus and the cytoplasm is regulated by the CCHC-type zinc finger. Upon UV-C stress stimulus, the nuclear concentration of the protein decreases, affecting alternative splicing.
    相似性Belongs to the SLU7 family.
    功能Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

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