- ￥2980
- Bioss
- bs-1387R-PE
- 2025年10月15日
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100ul
| 产品编号 | bs-1387R-PE |
| 英文名称 | HSP105 Rabbit pAb, PE conjugated |
| 中文名称 | PE标记的热休克蛋白105抗体 |
| 英文别名 | Antigen NY CO 25; Antigen NY-CO-25; heat shock 105kDa protein; heat shock 105kDa/110kDa protein 1; heat shock 110kDa protein; HS105_HUMAN; Heat shock 105kD alpha; Heat shock 105kD; Heat shock 105kD beta; Heat shock 105kDa protein 1; Heat shock 105kDa protein; Heat shock 105kDa/110kDa protein 1; Heat shock 110kDa protein; Heat shock protein 105 kDa; HSP105; HSP105A; HSP105B; HSP110; HSPH 1; HSPH1; KIAA0201; NY CO 25; Antigen NY CO 25; DKFZp686M05240. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human HSP105 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Protein Trafficking > Chaperones > Heat Shock Proteins |
| 亚基 | Interacts with HSPA8/HSC70. |
| 亚细胞定位 | Cytoplasm. |
| 组织特异性 | Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells. |
| 翻译后修饰 | Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity. |
| 相似性 | Belongs to the heat shock protein 70 family. |
| 功能 | Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities (By similarity). |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Heat Shock Proteins are ubiquitously expressed in all organisms. They are induced when a cell undergoes various types of environmental stresses like heat, cold and oxygen deprivation. They are characterized by their role as molecular chaperones.Heat shock protein (HSP) 105 exists as two isoforms; alpha and beta which belong to the HSP105/HSP110 protein family. HSP105 acts as both a chaperone to prevent thermal aggregation of proteins and as a regulator of mammalian cells. The HSP105 isoforms are found in the cytoplasm but not in the nucleoli under non-stressed and stressed conditions. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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HSP105 Rabbit pAb, PE conjugated(bs-1387R-PE)-100ul
￥2980
