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- Bioss
- bs-1712R-HRP
- 2026年10月17日
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100ul
| 产品编号 | bs-1712R-HRP |
| 英文名称 | Pan Cytokeratin Rabbit pAb, HRP conjugated |
| 中文名称 | HRP标记的广谱细胞角蛋白PCK抗体 |
| 英文别名 | pan-cytokeratin; pan-CK; pan CK; P-CK; CK-PAN; wide spectrum Cytokeratin; Cytokeratins; [cytokeratins 1, 2, 4, 5, 6, 7, 8, 71, 72, 75, 78]. |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human cytokeratins |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Intermediate Filaments > Class I > Cytokeratins |
| 亚细胞定位 | Cytoplasmic. |
| 组织特异性 | epithelial cells |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Cytokeratins are proteins of keratin-containing intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. The cytokeratins are encoded by a family encompassing 30 genes. Among them, 20 are epithelial genes and the remaining 10 are specific for trichocytes. In the cytoplasm, the keratin filaments conform a complex network which extends from the surface of the nucleus to the cell membrane. Numerous accessory proteins are involved in the genesis and maintenance of such structure. This association between the plasma membrane and the nuclear surface provides important implications for the organization of the cytoplasm and cellular communication mechanisms. Apart from the relatively static functions provided in terms of supporting the nucleus and providing tensile strength to the cell, the cytokeratin networks undergo rapid phosphate exchanges mediated depolymerization, with important implications in the more dynamic cellular processes such as mitosis and post-mitotic period, cell movement and differentiation. Cytokeratins interact with desmosomes and hemidesmosomes, thus collaborating to cell-cell adhesion and basal cell-underlying connective tissue connection. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
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文献和实验相关实验
calcitonin gene-related peptide 降钙素基因相关肽 CHAc choline acetylase 胆碱乙酰化酶 ChE cholinesterase 乙酰胆碱酯酶 CIg cytoplasmic immunoglobulin 胞浆免疫球蛋白 CK cytokeratin 细胞角蛋白 CLA common leukocyte antigen 白细胞共同抗原 CMV cytomegalovirus 巨细胞病毒 CNS
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pan CK | pan Cytokeratin Rabbit pAb, HRP conj.(bs-1712R-HRP)-100ul
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