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100ul
| 产品编号 | bs-17403R-HRP |
| 英文名称 | HIPK1 Rabbit pAb, HRP conjugated |
| 中文名称 | HRP标记的核小体相关激酶HIPK1抗体 |
| 英文别名 | Hipk 1; Hipk1; HIPK1_HUMAN; Homeodomain interacting protein kinase 1; Homeodomain interacting protein kinase 1 like protein; Homeodomain-interacting protein kinase 1; Myak; Nbak 2; Nbak2; Nuclear body associated kinase 2; Nuclear body associated kinase 2b. |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human HIPK1 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Epigenetics and Nuclear Signaling > Transcription > Other factors Signal Transduction > Protein Phosphorylation > Ser / Thr Kinases > Other Kinases |
| 亚细胞定位 | Nucleus. Cytoplasm. Predominantly nuclear. |
| 组织特异性 | Ubiquitously expressed with highest levels in skeletal muscle and heart. Overexpressed in breast cancer cell lines. |
| 翻译后修饰 | Autophosphorylated. Phosphorylated and activated by JNK1. |
| 相似性 | Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily. _x000D_ Contains 1 protein kinase domain. |
| 功能 | May play a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. May be involved in malignant squamous cell tumor formation. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene belongs to the Ser/Thr family of protein kinases and HIPK subfamily. It phosphorylates homeodomain transcription factors and may also function as a co-repressor for homeodomain transcription factors. Alternative splicing results in four transcript variants encoding four distinct isoforms. [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
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HIPK1 Rabbit pAb, HRP conj.(bs-17403R-HRP)-100ul
¥2980






