HNRNPM | hnRNP M1-M4 Rabbit pAb, AP conj.(bs-17335R-AP)-100ul产品图

HNRNPM | hnRNP M1-M4 Rabbit pA

b, AP conj.(bs-17335R-AP)-100ul
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  • bs-17335R-AP
  • 2026年10月14日
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    北京博奥森生物技术有限公司
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      100ul

    产品编号bs-17335R-AP
    英文名称hnRNP M1-M4 Rabbit pAb, AP conjugated
    中文名称AP标记的异质核糖核蛋白M1-M4抗体
    英文别名CEA receptor; CEAR; DKFZp547H118; Heterogeneous nuclear ribonucleoprotein M; Heterogeneous nuclear ribonucleoprotein M4; Heterogenous nuclear ribonucleoprotein M4; hnRNA binding protein M4; hnRNP M; Hnrnpm; HNRNPM4; HNRPM; HNRPM_HUMAN; HNRPM4; HTGR1; N acetylglucosamine receptor 1; NAGR1.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human hnRNP M1-M4
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Epigenetics and Nuclear Signaling > Chromatin Binding Proteins > DNA / RNA binding

    Epigenetics and Nuclear Signaling > DNA / RNA > DNA / Nucleotides

    Epigenetics and Nuclear Signaling > DNA / RNA > RNA Processing

    Epigenetics and Nuclear Signaling > DNA / RNA > RNA Processing > Splicing

    亚基Identified in the spliceosome C complex.
    亚细胞定位Nucleus, nucleolus.
    翻译后修饰Sumoylated.
    相似性Contains 3 RRM (RNA recognition motif) domains.
    功能Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}

     

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