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- Bioss
- bs-1766R-AP
- 2025年09月30日
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100ul
| 产品编号 | bs-1766R-AP |
| 英文名称 | FDC-SP Rabbit pAb, AP conjugated |
| 中文名称 | AP标记的滤泡树突细胞分泌蛋白抗体 |
| 英文别名 | ADC; FDC; FDCs; FDC-SP; FDCSP; Follicular dendritic cell; Follicular dendritic cell secreted protein; Follicular dendritic cell; Follicular dendritic cell secreted peptide; FDC secreted protein. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from rat FDC-SP |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Immunology > Secreted Molecules > Other secreted molecules |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Abundantly expressed in tonsil, lymph node, and trachea; strong expression in prostate; lower expression in thyroid, stomach, and colon. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Follicular dendritic cells are cells that facilitate antigen recognition by B cells in follicles. This kind of dendritic cell is not bone marrow derived and is not a kind of blood cell. It is purely a resident of the follicles of secondary lymphoid organs. B cells form germinal centers around follicular dendritic cells in lymphoid organs. Dendritic cells form from monocytes, white blood cells which circulate in the body and, depending on the right signal, can turn into dendritic cells or macrophages. The monocytes in turn are formed from stem cells in the bone marrow.In normal tissue this antibody identifies dendritic cells and a proportion of B lymphocytes. Evidence in pathological tissue and functional studies suggests it binds to an epitope expressed by antigen presenting cells. Within the macrophage/dendritic cell populations the epitope seen by RFD1 is coexpressed with RFD7 by a subset of cells that exhibit suppressive activity on T cell stimulation. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
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文献和实验Transient Transfection of Schneider Cells in the Study of Transcription Factors
functional domains of AP-2 (2 ), Sp1 (3 ,4 ) and CTF/NF-I (5 ).
的GR可结合于AP-1从而抑制胶原酶的合成。AP-1还参与T细胞的活化，促进IL-2及IL-2R基因的表达等，GC则通过GR的活化而AP-1的活性以对抗细胞因子的作用。其它转录因子如NF-κB及NF-AT等也受GC的负性调控。此领域的研究将对合理的药物设计及相关的临床实践具有指导意义。 2.龙激素 一般而言，睾酮等雄激不经对免疫功能有抑制性作用。睾酮可减少人泪腺中IgA的产生，这一作用为雄激素所独有。在睾酮的作用下，胸腺的重量和体积均减少。小鼠迟发型皮肤超敏反应及抗体的生成亦受睾酮的抑制
SDS-PA gels, and subsequent detection of proteins using rabbit antisera and alkaline phosphatase-conjugated goat-anti-rabbit IgG, detected using bromo-chloro-indolyl phosphate (BCIP) and Nitro-blue tetrazolium (NBT) salts. ・
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