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CD46 Rabbit pAb, PerCP-Cy7 con

jugated(bs-1529R-PerCP-Cy7)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-1529R-PerCP-Cy7
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-1529R-PerCP-Cy7
    英文名称CD46 Rabbit pAb, PerCP-Cy7 conjugated
    中文名称PerCP-Cy7标记的膜辅蛋白抗体
    英文别名CD46 antigen; CD46 molecule; CD46 molecule complement regulatory protein; Complement membrane cofactor protein; MCP; Measles virus receptor; Membrane cofactor protein; Membrane cofactor protein precursor; MIC 10; MIC10; TLX; TRA2.10; Trophoblast leucocyte common antigen; Trophoblast lymphocyte cross reactive antigen; Antigen identified by monoclonal antibody TRA 2 10; MCP_HUMAN; membrane cofactor protein isoform 1 precursor.
    产品应用Flow-Cyt=1μg /test, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human CD46
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA and 0.02% Proclin300.
    研究领域

    Immunology > Cell Type Markers > CD > Non-lineage

    Immunology > Innate Immunity > Complement > Regulatory

    亚基Interacts with C3b and C4b. Binds to Measles virus H protein, to Human herpesvirus 6 GH protein and to human adenovirus B/D PIV/fiber protein, and acts as a receptor for these viruses. Binds to Streptococcus pyogenes M protein and to type IV pili from Neisseria, and may act as a receptor for these pathogenic bacteria.
    亚细胞定位Isoform 1: Cytoplasmic vesicle, secretory vesicle, acrosome inner membrane; Single-pass type I membrane protein. Note=Inner acrosomal membrane of spermatozoa.
    _x000D_ Isoform 2: Secreted (Probable).
    组织特异性Present only in testis (at protein level).
    翻译后修饰May be O-glycosylated (By similarity).
    _x000D_ N-glycosylated.
    相似性Contains 4 Sushi (CCP/SCR) domains.
    功能May be involved in the fusion of the spermatozoa with the oocyte during fertilization.
    保存条件Store at 2-8°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料CD46 is one of the membrane complement regulatory proteins. CD46 possesses C3b-binding and factor I cofactor activities which play important roles in the regulation of the complement activation pathway. CD46 is widely distributed on blood cells, endothelial cells, epithelial cells and tumor cell lines. CD46 exists as many isoforms in a variety of tissues. The antigen has a broad distribution and is present on leukocytes, platelets, endothelial cells, epithelial cells and fibroblasts. It is strongly expressed on salivary gland ducts and kidney ducts, moderately on lymphocytes and endothelium, and weakly on interstitial tissues and muscle cells, but not on erythrocytes. It is expressed on thymocytes, B cells, monocytes, granulocytes, NK cells, platelets, epithelial and endothelial cells.

     

    应用推荐稀释比例
    {Flow-Cyt}{1μg /test}
    {IF}{1:100-500}

     

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    图标文献和实验
    相关实验
    • Fluorochrome Absorption and Emission Spectra

      . Using a 650 nm longpass filter will give optimum detection for this fluorochrome. The emitted light is collected in the fluorescence-3 (FL3) channel. PerCP-Cy5.5 is recommended for use with stream-in-air flow cytometers. APC-Cy7

    • Fluorochrome Absorption and Emission

      . Using a 650 nm longpass filter will give optimum detection for this fluorochrome. The emitted light is collected in the fluorescence-3 (FL3) channel. PerCP-Cy5.5 is recommended for use with stream-in-air flow cytometers. APC-Cy7

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