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- bs-13263R-Cy7
- 2025年09月30日
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100ul
| 产品编号 | bs-13263R-Cy7 |
| 英文名称 | GAD65 + GAD67 Rabbit pAb, Cy7 conjugated |
| 中文名称 | Cy7标记的谷氨酸脱羧酶65+谷氨酸脱羧酶67抗体 |
| 英文别名 | GAD-65/67; GAD-65/67; 65 kDa glutamic acid decarboxylase; DCE 2; DCE2; GAD 2; GAD 65; GAD-2; GAD-65; GAD 65; GAD2; Glutamate Decarboxylase 2(pancreatic islets and brain 65kDa); Glutamate Decarboxylase 2; Glutamate Decarboxylase 65; Glutamate decarboxylase 65 kDa isoform; Glutamic Acid Decarboxylase 2; Glutamic Acid Decarboxylase 65; Glutamate decarboxylase 1; 67 kDa glutamic acid decarboxylase; GAD-67; Glutamate decarboxylase 67 kDa isoform.DCE1_HUMAN; DCE2_HUMAN. |
| 产品应用 | IF=1:100-500, ICC/IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human GAD65 + GAD67 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Metabolism > Pathways and Processes > Metabolic signaling pathways > Amino acid metabolism Neuroscience > Neurology process > Metabolism Neuroscience > Neurotransmitter > Amino Acids > Glutamate |
| 亚基 | Homodimer. |
| 亚细胞定位 | Cytoplasm, cytosol. Cytoplasmic vesicle. Cell junction, synapse, presynaptic cell membrane; Lipid-anchor. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associated to cytoplasmic vesicles. In neurons, cytosolic leaflet of Golgi membranes and presynaptic clusters. |
| 翻译后修饰 | Phosphorylated; which does not affect kinetic parameters or subcellular location._x000D_
Palmitoylated; which is required for presynaptic clustering. |
| 相似性 | Belongs to the group II decarboxylase family. |
| 功能 | Catalyzes the production of GABA. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008] |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
| {ICC/IF} | {1:100-500} |
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GAD65 + GAD67 Rabbit pAb, Cy7 conjugated(bs-13263R-Cy7)-100ul
￥2980
