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- Bioss
- bs-19719R-Bio
- 2026年10月14日
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- 技术资料
- 规格：
100ul
| 产品编号 | bs-19719R-Bio |
| 英文名称 | RAB7L1 Rabbit pAb, Biotin conjugated |
| 中文名称 | Biotin标记的ras基因相关蛋白RAB7样蛋白1抗体 |
| 英文别名 | RAB7L_HUMAN; RAB29; DKFZp686P1051; Rab 7 like protein 1; RAB 7L; Rab7 like protein 1; RAB7 member RAS oncogene family like 1; RAB7L; Ras related protein Rab 7L1; Ras-related protein Rab-7L1; Ras related protein Rab7L1. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human RAB7L1 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Signaling Pathway > G Protein Signaling > Small G Proteins > Ras Family |
| 亚细胞定位 | Cell membrane; Lipid-anchor; Cytoplasmic side. |
| 翻译后修饰 | In case of Salmonella enterica serovar Typhimurium (S.Typhimurium) infection, is proteolytically cleaved between Gly-41 and Val-42 by the GtgE viral protease encoded on the Gifsy-2 lysogen bacteriophage, which therefore prevents the recruitment of RAB29 to S.Typhimurium-containing vacuoles. In contrast, no proteolytically cleavage is detected in S.Typhi-infected cells (PubMed:22042847). |
| 相似性 | Belongs to the small GTPase superfamily. Rab family. |
| 功能 | Rab GTPase key regulator in vesicle trafficking. Essential for maintaining the integrity of the endosome-trans-Golgi network structure. Together with LRRK2, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS). May play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S.Typhi) epithelial cell infection. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
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RAB29 | RAB7L1 Rabbit pAb, Biotin conj.(bs-19719R-Bio)-100ul
￥2980
