- ￥2980
- Bioss
- bs-13734R-Bio
- 2025年09月30日
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100ul
| 产品编号 | bs-13734R-Bio |
| 英文名称 | Connexin 31.1 Rabbit pAb, Biotin conjugated |
| 中文名称 | Biotin标记的间隙连接蛋白31.1/GJB5抗体 |
| 英文别名 | Connexin 31.1; Connexin-31.1; Connexin31.1; Cx31.1; CXB5_HUMAN; Gap junction beta 5 protein; Gap junction beta-5 protein; Gap junction protein beta 5 31.1kDa; Gap junction protein beta 5; GJB 5; GJB5. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Connexin 31.1 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚细胞定位 | Cell membrane. Cell junction > gap junction. |
| 相似性 | Belongs to the connexin family. Beta-type (group I) subfamily. |
| 功能 | One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neiGHBoring cell. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The connexin family of proteins form hexameric complexes, called connexons, that facilitate movement of low molecular weight proteins between cells via gap junctions. Connexin proteins share a common topology of four transmembrane ?helical domains, two extracellular loops, a cytoplasmic loop and cytoplasmic N- and C-termini. Many of the key functional differences arise from specific amino acid substitutions in the most highly conserved domains; the transmembrane and extracellular regions. Connexin 31.1, Cx31.1 or Gap junction beta-5 protein, is a 271 amino acid protein that is predominantly expressed in skin with lower expression in testis. Expression of connexin 31.1 is required for normal placental development in mice. Down-regulation of the connexin 31.1 gene correlates with head and neck squamous cell carcinomas (HNSCC) and therefore it may be a potential therapeutic target. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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Connexin 31.1 Rabbit pAb, Biotin conjugated(bs-13734R-Bio)-100ul
￥2980
