- ￥2980
- Bioss
- bs-11094R-BF594
- 2025年09月30日
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100ul
| 产品编号 | bs-11094R-BF594 |
| 英文名称 | NCAM2 Rabbit pAb, BF594 conjugated |
| 中文名称 | BF594标记的神经细胞粘附分子2抗体 |
| 英文别名 | N CAM 2; N CAM 21; N CAM2; N CAM21; N-CAM-2; NCAM 2; NCAM 21; NCAM-2; Ncam2; NCAM2_HUMAN; NCAM21; Neural cell adhesion molecule 2; OCAM GPI; R4B12; RB 8 neural cell adhesion molecule; RB8 neural cell adhesion molecule; RNCAM. |
| 产品应用 | Flow-Cyt=3ug/test Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human NCAM2 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Neuroscience > Cell Adhesion Proteins > Membrane Proteins Neuroscience > Neurology process > Neural Signal Transduction Neuroscience > Sensory System > Olfactory system |
| 亚基 | Contains 2 fibronectin type-III domains. Contains 5 Ig-like C2-type (immunoglobulin-like) domains. |
| 亚细胞定位 | Cell membrane. |
| 组织特异性 | Expressed most strongly in adult and fetal brain. |
| 相似性 | Contains 2 fibronectin type-III domains. Contains 5 Ig-like C2-type (immunoglobulin-like) domains. |
| 功能 | May play important roles in selective fasciculation and zone-to-zone projection of the primary olfactory axons. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | NCAM2 is an 837 amino acid protein encoded by the human gene NCAM2. NCAM2 contains five immunoglobulin-like domains, two Fibronectin type III domains, a transmembrane domain and a cytoplasmic domain. The gene is expressed most strongly in human adult and fetal brain. NCAM2 is a member of the neural cell adhesion molecule (NCAM) family. NCAMs are closely related cell surface glycoproteins involved in cell to cell interactions during growth and are thought to play an important role in embryogenesis and development. NCAM2 is a considered a good candidate for involvement in certain Down syndrome phenotypes because a slight overexpression of NCAMs increases many-fold the homotypic adhesion properties of cells. Stat5 regulates NCAM2 in vivo by binding to the NCAM2 intron in the NKL natural killer cell line; this binding is induced by cytokines that activate Stat5. Neither Stat1 nor Stat3 bind to this region, despite sharing a consensus binding sequence with Stat5. |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {3ug/test} |
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NCAM2 Rabbit pAb, BF594 conjugated(bs-11094R-BF594)-100ul
￥2980
