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TACC2 Rabbit pAb, Biotin conju

gated(bs-5736R-Bio)-100ul
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  • ￥2980
  • Bioss已认证
  • bs-5736R-Bio
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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北京博奥森生物技术有限公司
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    产品编号bs-5736R-Bio
    英文名称TACC2 Rabbit pAb, Biotin conjugated
    中文名称Biotin标记的转化酸性卷曲含蛋白质2
    英文别名TACC2_HUMAN; Anti zuai 1; AZU 1; AZU1; ECTACC; TACC 2; Transforming acidic coiled coil containing protein 2.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human TACC2
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Cell cycle > Cell division

    Cell Biology > Cell Cycle > Cell Division > Centromere

    Tags & Cell Markers > Subcellular Markers > Organelles > Centrosome

    亚基Interacts with CCDC100/CEP120 (By similarity). Interacts with microtubules. Interacts with YEATS4, GCN5L2 and PCAF.
    亚细胞定位Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, centrosome.
    组织特异性Strongly expressed in heart, skeletal muscle, brain, prostate, thyroid and trachea.
    翻译后修饰Phosphorylated by TTK; which is required for localization in centrosome.
    相似性Belongs to the TACC family.
    Contains 1 SPAZ (Ser/Pro-rich AZU-1) domain.
    功能Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity). May play a role in organizing centrosomal microtubules. May act as a tumor suppressor protein. May represent a tumor progression marker.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料TACC2 is a conserved family of centrosome and microtubule interacting proteins that are implicated in cancer. This gene encodes a protein that concentrates at centrosomes throughout the cell cycle. This gene lies within a chromosomal region associated with tumorigenesis. Expression of this gene is thought to affect the progression of breast tumors. Expression of this gene is also induced by erythropoietin.

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}

     

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