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- bs-4610R-AP
- 2026年10月14日
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- 技术资料
- 规格：
100ul
| 产品编号 | bs-4610R-AP |
| 英文名称 | phospho-AQP2 (Ser264+261) Rabbit pAb, AP conjugated |
| 中文名称 | AP标记的磷酸化水通道蛋白2抗体 |
| 英文别名 | Aquaporin 2(phospho S261); p-Aquaporin 2(phospho S261) ADH water channel; AQP 2; AQP CD; AQP2; AQPCD; Aquaporin 2 collecting duct; Aquaporin CD; Aquaporin2; Aquaporine 2; Collecting duct water channel protein; MGC34501; Water channel protein for renal collecting duct; WCH CD; WCHCD. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthesised phosphopeptide derived from human AQP2 around the phosphorylation site of Ser264/261 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Metabolism > Plasma Membrane > Channels |
| 亚细胞定位 | Apical cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Shuttles from vesicles to the apical membrane. |
| 组织特异性 | Expressed in renal collecting tubules. |
| 翻译后修饰 | Ser-256 phosphorylation is necessary and sufficient for expression at the apical membrane. Endocytosis is not phosphorylation-dependent. |
| 相似性 | Belongs to the MIP/aquaporin (TC 1.A.8) family. |
| 功能 | Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a water channel protein located in the kidney collecting tubule. It belongs to the MIP/aquaporin family, some members of which are clustered together on chromosome 12q13. Mutations in this gene have been linked to autosomal dominant, and recessive forms of nephrogenic diabetes insipidus. Belongs to the MIP/aquaporin (TC 1.A.8) family. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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AQP2 (p-S264/261) Rabbit pAb, AP conj.(bs-4610R-AP)-100ul
￥2980
