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- Bioss
- bs-7828R-Bio
- 2025年09月30日
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100ul
| 产品编号 | bs-7828R-Bio |
| 英文名称 | RINT1 Rabbit pAb, Biotin conjugated |
| 中文名称 | Biotin标记的胞膜间内质网调节蛋白1抗体 |
| 英文别名 | HsRINT 1; HsRINT1; RAD50 interacting protein 1; RINT 1; RINT1_HUMAN. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human RINT1 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Oncoproteins/suppressors > Tumor suppressors Cell Biology > Cell Cycle > Cell Division > Other cell division antibodies Epigenetics and Nuclear Signaling > Chromosome Structure > Telomeres Signal Transduction > Protein Trafficking > Vesicle Transport > Regulation |
| 亚基 | Associated with a SNARE complex consisting of STX18,USE1L, BNIP1/SEC20L, and SEC22B. Interacts directly withBNIP1/SEC20L and ZW10. Interacts with RAD50 during late S and G2/Mphases. Interacts with RBL2, preferentially with the active,hypophosphorylated form. |
| 亚细胞定位 | Cytoplasm. Endoplasmic reticulum membrane;Peripheral membrane protein._x000D_ |
| 相似性 | Belongs to the RINT1 family. Contains 1 RINT1/TIP20 domain._x000D_ |
| 功能 | Involved in regulation of membrane traffic between theGolgi and the endoplasmic reticulum. May play a role in cell cyclecheckpoint control. Essential for telomere length control. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | RINT1 is involved in the regulation of membrane traffic between the golgi and the endoplasmic reticulum. It may play a role in cell cycle checkpoint control and is essential for telomere length control. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
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文献和实验- or triple-labeling immunofluorescence, it is necessary to use primary antibodies raised in different host species such as mouse, rabbit, and goat. However, in many cases, suitable primary antibodies raised in different species are unavailable
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