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- bs-7828R-AP
- 2025年09月30日
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100ul
| 产品编号 | bs-7828R-AP |
| 英文名称 | RINT1 Rabbit pAb, AP conjugated |
| 中文名称 | AP标记的胞膜间内质网调节蛋白1抗体 |
| 英文别名 | HsRINT 1; HsRINT1; RAD50 interacting protein 1; RINT 1; RINT1_HUMAN. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human RINT1 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Oncoproteins/suppressors > Tumor suppressors Cell Biology > Cell Cycle > Cell Division > Other cell division antibodies Epigenetics and Nuclear Signaling > Chromosome Structure > Telomeres Signal Transduction > Protein Trafficking > Vesicle Transport > Regulation |
| 亚基 | Associated with a SNARE complex consisting of STX18,USE1L, BNIP1/SEC20L, and SEC22B. Interacts directly withBNIP1/SEC20L and ZW10. Interacts with RAD50 during late S and G2/Mphases. Interacts with RBL2, preferentially with the active,hypophosphorylated form. |
| 亚细胞定位 | Cytoplasm. Endoplasmic reticulum membrane;Peripheral membrane protein._x000D_ |
| 相似性 | Belongs to the RINT1 family. Contains 1 RINT1/TIP20 domain._x000D_ |
| 功能 | Involved in regulation of membrane traffic between theGolgi and the endoplasmic reticulum. May play a role in cell cyclecheckpoint control. Essential for telomere length control. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | RINT1 is involved in the regulation of membrane traffic between the golgi and the endoplasmic reticulum. It may play a role in cell cycle checkpoint control and is essential for telomere length control. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
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文献和实验SDS-PA gels, and subsequent detection of proteins using rabbit antisera and alkaline phosphatase-conjugated goat-anti-rabbit IgG, detected using bromo-chloro-indolyl phosphate (BCIP) and Nitro-blue tetrazolium (NBT) salts. ・
Developing Genetically Engineered Mouse Models to Study Tumor Suppression
Literature Cited Armstrong, J.F., Kaufman, M.H., Harrison, D.J., and Clarke, A.R. 1995. High‐frequency developmental abnormalities in p53‐deficient mice. Curr
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