- ￥2980
- Bioss
- bs-13682R-HRP
- 2025年09月30日
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100ul
| 产品编号 | bs-13682R-HRP |
| 英文名称 | WDR68 Rabbit pAb, HRP conjugated |
| 中文名称 | HRP标记的WDR68蛋白抗体 |
| 英文别名 | AN11; Dcaf7; DCAF7_HUMAN; DDB1-and CUL4-associated factor 7; HAN11; Human anthocyanin; Petunia; Seven WD repeat protein of the AN11 family 1; SWAN 1; WD repeat domain 68; WD repeat protein An11 homolog; WD repeat-containing protein 68; WD repeat-containing protein An11 homolog; WDR68. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human WDR68 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cell Biology > Other Antibodies > Other Antibodies Signal Transduction > Adapters > Cytoplasmic |
| 亚基 | Interacts with DYRK1A, DYRK1B and DIAPH1. Interacts with DDB1. Interacts with ZNF703. |
| 亚细胞定位 | Cytoplasm. Nucleus. Overexpression of DIAHP1 or active RHOA causes translocation from the nucleus to cytoplasm. |
| 翻译后修饰 | Protein modification; protein ubiquitination. |
| 相似性 | Belongs to the WD repeat DCAF7 family. _x000D_ Contains 4 WD repeats. |
| 功能 | Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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WDR68 Rabbit pAb, HRP conjugated(bs-13682R-HRP)-100ul
￥2980
