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产品信息以Bioss网站为准
- 规格:
100ul
| 产品编号 | bs-13671R-Bio |
| 英文名称 | TRAF6BP Rabbit pAb, Biotin conjugated |
| 中文名称 | Biotin标记的肿瘤坏死因子受体相关蛋白6结合蛋白抗体 |
| 英文别名 | 1200003J11Rik; 1700069J21Rik; Aa1076; AA930106; CALCOCO 3; CALCOCO3; D6Ertd404e; D6Ertd772e; Human T cell leukemia virus type 1-binding protein; Liver regeneration-related protein LRRG004; MGC94031; PRO0105; T6BP; Tax1(human T cell leukemia virus type I) binding protein 1; Tax1(human T cell leukemia virus type I) binding protein; Tax1 binding protein 1; Tax1 binding protein; Tax1-binding protein 1; Tax1-binding protein 1 homolog; TAX1BP1; TAX1BP1 protein; tax1bp1b; TAXB1_HUMAN; TRAF 6 binding protein; TRAF6 binding protein; TRAF6 binding protein T6BP; TRAF6-binding protein; TRAF6-interacting protein; TXBP 151; TXBP151; wu:fc20c12; wu:fc56e11; zgc:73219; zgc:77129. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human TRAF6BP |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Adapters > Cytoplasmic |
| 亚基 | Homooligomer. Interacts with TRAF6 in a IL-1-dependent manner. Interacts with TNFAIP3. Interacts with STARD13. Interacts with the HTLV-1 protein Tax-1. |
| 组织特异性 | Expressed in all tissues tested. |
| 翻译后修饰 | Phosphorylated in the C-terminal region by CHUK/IKKA leading to NF-kappa-B signaling down-regulation. |
| 功能 | Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
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文献和实验相关实验
- or triple-labeling immunofluorescence, it is necessary to use primary antibodies raised in different host species such as mouse, rabbit, and goat. However, in many cases, suitable primary antibodies raised in different species are unavailable
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TRAF6BP Rabbit pAb, Biotin conjugated(bs-13671R-Bio)-100ul
¥2980









