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100ul
| 产品编号 | bs-0384R-PE |
| 英文名称 | GLUT4 Rabbit pAb, PE conjugated |
| 中文名称 | PE标记的葡萄糖转运蛋白4抗体 |
| 英文别名 | insulin-responsive; Glucose transporter GLUT 4; Glucose Transporter GLUT4; Glucose transporter type 4; Glucose transporter type 4 insulin responsive; GLUT 4; GLUT-4; GTR4_HUMAN; kug; SLC 2A4; SLC2A4; solute carrier family 2(facilitated glucose transporter) member 4; Solute carrier family 2, facilitated glucose transporter member 4. |
| 产品应用 | Flow-Cyt=1μg/Test, IF=1:100-500, ICC/IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human GLUT4 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Cancer Metabolism > Metabolic signaling pathway > Metabolism of carbohydrates Cardiovascular > Heart > Cardiac metabolism Metabolism > Pathways and Processes > Metabolic signaling pathways > Carbohydrate metabolism Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism Metabolism > Types of disease > Diabetes Signal Transduction > Metabolism > Energy Metabolism Stem Cells > Mesenchymal Stem Cells > Adipogenesis |
| 亚细胞定位 | Endomembrane system. Cytoplasm > perinuclear region. Localizes primarily to the perinuclear region, undergoing continued recycling to the plasma membrane where it is rapidly reinternalized. The dileucine internalization motif is critical for intracellular sequestration. |
| 组织特异性 | Skeletal and cardiac muscles; brown and white fat. |
| 翻译后修饰 | Sumoylated. |
| 相似性 | Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. |
| 功能 | Insulin-regulated facilitative glucose transporter. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | GLUT4 is the facilitated glucose transporter expressed exclusively in adipocytes and muscle cells, and is also known as the "insulin-responsive" glucose transporter. GLUT4 translocates from an ill-defined intracellular compartment to the plasma membrane in response to insulin. The total cellular content of GLUT4 is significantly decreased in adipose cells from many patients with Type II diabetes mellitus, and animals with some types of experimental diabetes. |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {1μg/Test} |
| {IF} | {1:100-500} |
| {ICC/IF} | {1:100-500} |
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GLUT4 Rabbit pAb, PE conjugated(bs-0384R-PE)-100ul
¥2980







