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- bs-23053R-Bio
- 2025年09月30日
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100ul
| 产品编号 | bs-23053R-Bio |
| 英文名称 | IL17RA Rabbit pAb, Biotin conjugated |
| 中文名称 | Biotin标记的白介素17受体抗体 |
| 英文别名 | Interleukin-17 receptor A; IL-17 receptor A; IL-17RA; hIL-17R; IL-17R; MGC10262; CD217; CDw217; IL17 RECEPTOR; IL17FR; AW538159; I17RA_HUMAN. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from mouse IL-17R/IL-17RA/CD217 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Immunology > Innate Immunity > Cytokines > Interleukins Immunology > Innate Immunity > Macrophage / Inflamm. |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 组织特异性 | Widely expressed. |
| 翻译后修饰 | Glycosylated. |
| 相似性 | Contains 1 SEFIR domain. |
| 功能 | Receptor for IL17A and IL17F. Binds its IL17A ligand with low affinity, suggesting that additional components are involved in IL17A-induced signaling. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. [provided by RefSeq] |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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文献和实验相关实验
- or triple-labeling immunofluorescence, it is necessary to use primary antibodies raised in different host species such as mouse, rabbit, and goat. However, in many cases, suitable primary antibodies raised in different species are unavailable
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IL17RA Rabbit pAb, Biotin conjugated(bs-23053R-Bio)-100ul
￥2980
