calcium-activated chloride channel CLCA4 Rabbit pAb, AP conjugated(bs-1585R-AP)-100ul

calcium-activated chloride cha

nnel CLCA4 Rabbit pAb, AP conjugated(bs-1585R-AP)-100ul
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  • ￥2980
  • Bioss已认证
  • bs-1585R-AP
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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北京博奥森生物技术有限公司
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    产品编号bs-1585R-AP
    英文名称calcium-activated chloride channel CLCA4 Rabbit pAb, AP conjugated
    中文名称AP标记的氯化钙通道活性的4抗体
    英文别名Clca3b; Clca4; Clca3b chloride channel calcium activated 3B; chloride channel calcium activated 3B precursor; chloride channel calcium activated 4.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from mouse chloride channel calcium activated 3B precursor
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Signal Transduction > Metabolism > Plasma Membrane > Channels

    亚细胞定位Cell membrane; Single-pass membrane protein. Apical cell membrane. Secreted. Note=The C-terminus 30 kDa form is anchored to the membrane. The N-terminus 110 kDa form is released from the membrane triggered by an unknown stimulus. Associated with the microvilli of non-goblet cell enterocytes in the small and large intestine. Co-localizes with CFTR.
    组织特异性Primarily expressed in the digestive tract, mainly in colon. Detected in smaller amounts in brain, urogenital organs, testis, and salivary and mammary glands. Highly expressed in the epithelial layer and submucosal gland of the inferior turbinate mucosa. Lower levels in the epithelial layer of nasal polyp.
    翻译后修饰N-Glycosylated._x000D_
    Processed at a monobasic residue to yield a larger N-terminal and a smaller C-terminal cleavage products of 90 to 110 and 30 to 35 kDa, respectively.
    相似性Belongs to the CLCR family._x000D_
    Contains 1 VWFA domain.
    功能May be involved in mediating calcium-activated chloride conductance.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene belongs to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions. Alternative splicing results in multiple transcript variants, only one of which is thought to be protein coding. [provided by RefSeq, Dec 2008]

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

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