- ￥2980
- Bioss
- bs-6299R-Bio
- 2025年09月30日
- 产品信息以Bioss网站为准
企业认证
相关产品推荐更多 >
Geminin Rabbit pAb, BF488 conjugated(bs-9536R-BF488)-100ul
￥2980
FAM3C Rabbit pAb, HRP conjugated(bs-7862R-HRP)-100ul
￥2980
DYX1C1 Rabbit pAb(bs-13043R)-50ul/100ul/200ul
￥1180phospho-ERK1/ERK2(phospho-T183/Y185) Rabbit pAb, PE-Cy7 conjugated(bs-1522R-PE-Cy7)-100ul
￥2980MPO Rabbit pAb, Cy7 conjugated(bs-41105R-Cy7)-100ul
￥2980
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
100ul
| 产品编号 | bs-6299R-Bio |
| 英文名称 | DRES17 Rabbit pAb, Biotin conjugated |
| 中文名称 | Biotin标记的乳腺癌相关蛋白DRES17抗体 |
| 英文别名 | DRES17; Drosophila-related expressed sequence 17; hprune; HTCD37; Prune homolog; PRUNE like protein; TcD37 homolog; PRUNE_HUMAN. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human DRES17 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Oncoproteins/suppressors > Oncoproteins > Cell survival & death Cancer > Tumor biomarkers > Oncoproteins Tags & Cell Markers > Cell Type Markers > Tumor Associated |
| 亚基 | Homooligomer. Able to homodimerize via its C-terminal domain. Interacts with NME1. Interacts with GSK3; at focal adhesion complexes where paxillin and vinculin are colocalized. |
| 亚细胞定位 | Cytoplasm. Nucleus. Cell junction, focal adhesion. Note=In some transfected cells a nuclear staining is also observed. |
| 组织特异性 | Ubiquitously expressed. Seems to be overexpressed in aggressive sarcoma subtypes, such as leiomyosarcomas and malignant fibrous histiocytomas (MFH) as well as in the less malignant liposarcomas. |
| 相似性 | Belongs to the PPase class C family. Prune subfamily. |
| 功能 | Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, is able to induce cell motility and acts as a negative regulator of NME1. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | PRUNE, the human homologue of the Drosophila gene, is located in 1q21.3, a region highly amplified in human sarcomas, malignant tumours of mesenchymal origin. Human prune (h-prune), a phosphoesterase DHH family appertaining protein, physically interacts with nm23-H1, a metastasis suppressor gene. h-prune is involved in cellular motility and metastasis formation. Metastatic breast cancers were found to overexpress h-prune; h-prune was also found to be highly expressed in colorectal and pancreatic cancers. Hence h-prune is considered useful as a marker for tumor aggressiveness. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验), as well as semithin sections of Epon (17 ) and Lowicryl K4M-embedded tissues (18 ,19 ), However, in order to achieve a visible pink staining, which is the natural color of particles of colloidal gold in transmitted visible light (20 ), highly concentrated lectin
- or triple-labeling immunofluorescence, it is necessary to use primary antibodies raised in different host species such as mouse, rabbit, and goat. However, in many cases, suitable primary antibodies raised in different species are unavailable
PRINS for the Detection of Gene Deletions in Cancer
and extended in the presence of the four trinucleotide precursors, biotin-16-dUTP, and Taq DNA polymerase. After addition of avidin-conjugated fluorophores, the resulting signals could be visualized by fluorescence microscopy in metaphase spreads and interphase
技术资料暂无技术资料 索取技术资料
