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LONP1 Rabbit pAb, Biotin conju

gated(bs-4245R-Bio)-100ul
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  • ￥2980
  • Bioss已认证
  • bs-4245R-Bio
  • 2026年02月11日
  • 产品信息以Bioss网站为准
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    产品编号bs-4245R-Bio
    英文名称LONP1 Rabbit pAb, Biotin conjugated
    中文名称Biotin标记的线粒体离子肽酶1抗体
    英文别名Serine protease 15; hLON ATP dependent protease; Lon protease like protein; LonHS; LONP; PIM1; PRSS15; hLON; LON; lon peptidase 1, mitochondrial; LON protease; Mitochondrial ATP dependent protease Lon; Mitochondrial Ion peptidase 1; Protease serine 15.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human LONP1
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Cancer Metabolism > Response to hypoxia

    Epigenetics and Nuclear Signaling > DNA / RNA > Translation > Mito. Translation

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Nucleotide metabolism

    Metabolism > Pathways and Processes > Metabolism processes > Hypoxia

    亚基Homohexamer or homoheptamer. Organized in a ring with a central cavity. DNA and RNA binding is stimulated by substrate and inhibited by ATP binding. Interacts with PEO1 and mitochondrial DNA polymerase subunit POLG.
    亚细胞定位Mitochondrion matrix.
    组织特异性Duodenum, heart, lung and liver, but not thymus.
    相似性Belongs to the peptidase S16 family.
    Contains 1 Lon domain.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料LONP1 encodes a mitochondrial matrix protein in the Lon family of ATP dependent proteases. It binds a specific sequence in the light and heavy chain promoters of the mitochondrial genome which are involved in regulation of DNA replication and transcription.

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}

     

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