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- bs-0199R-AP
- 2026年02月09日
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100ul
| 产品编号 | bs-0199R-AP |
| 英文名称 | GFAP Rabbit pAb, AP conjugated |
| 中文名称 | AP标记的胶质纤维酸性蛋白抗体 |
| 英文别名 | Astrocyte Marker; FLJ45472; GFAP; Glial Fibrillary Acidic Protein; Intermediate filament protein; GFAP_HUMAN. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:200-1000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human GFAP |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Neuroscience > Cell Adhesion Proteins > Cytoskeletal Proteins > Intermediate Filaments Neuroscience > Cell Type Marker > Glia marker > Astrocyte marker Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Intermediate Filaments > Class II > GFAP Stem Cells > Neural Stem Cells > Glial Restricted Lineage > Astrocyte Tags & Cell Markers > Cell Type Markers > Neuroscience Markers > Glial |
| 亚基 | Interacts with SYNM. Isoform 3 interacts with PSEN1 (via N-terminus). |
| 亚细胞定位 | Cytoplasm. Note=Associated with intermediate filaments. |
| 组织特异性 | Expressed in cells lacking fibronectin. |
| 翻译后修饰 | Phosphorylated by PKN1. |
| 相似性 | Belongs to the intermediate filament family. |
| 功能 | GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008] |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:200-1000} |
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文献和实验SDS-PA gels, and subsequent detection of proteins using rabbit antisera and alkaline phosphatase-conjugated goat-anti-rabbit IgG, detected using bromo-chloro-indolyl phosphate (BCIP) and Nitro-blue tetrazolium (NBT) salts. ・
; Glires; Rodentia; Sciurognathi; Muridae; Murinae; Rattus. REFERENCE 1 (bases 1 to 1600) AUTHORS Di Filippo,C., Marfella,R., Cuzzocrea,S., Piegari,E., Petronella,P., Giugliano,D., Rossi,F. and D'Amico,M. TITLE Hyperglycemia in streptozotocin-induced
Developing Genetically Engineered Mouse Models to Study Tumor Suppression
Literature Cited Armstrong, J.F., Kaufman, M.H., Harrison, D.J., and Clarke, A.R. 1995. High‐frequency developmental abnormalities in p53‐deficient mice. Curr
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