- ￥2980
- Bioss
- bs-2577R-Bio
- 2026年01月17日
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100ul
| 产品编号 | bs-2577R-Bio |
| 英文名称 | GNLY Rabbit pAb, Biotin conjugated |
| 中文名称 | Biotin标记的颗粒溶素抗体 |
| 英文别名 | Granulysin; D2S69E; LAG2; 519; LAG 2; Lymphocyte activation gene 2; Lymphokine LAG 2; NKG 5; NKG5; Protein NKG5; T cell activation protein 519; T lymphocyte activation gene 519; TLA519. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human GNLY/NKG5 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Immunology > Adaptive Immunity > T Cells > Cytotoxic Cells Immunology > Innate Immunity > NK Cells |
| 亚细胞定位 | Secreted. Note=Located in the cytotoxic granules of T-cells, which are released upon antigen stimulation. |
| 组织特异性 | Expressed in natural killer and T-cells. |
| 翻译后修饰 | A 9 kDa form is produced by proteolytic processing of a 15 kDa protein. |
| 相似性 | Contains 1 saposin B-type domain. |
| 功能 | Antimicrobial protein that kills intracellular pathogens. Active against a broad range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | GNLY (granulysin) is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. GNLY has antimicrobial activity against M.tuberculosis and other organisms including Gram-positive and Gram-negative bacteria, fungi, and parasites. Alternatively spliced transcript variants encoding different isoforms have been identified. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
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文献和实验相关实验
- or triple-labeling immunofluorescence, it is necessary to use primary antibodies raised in different host species such as mouse, rabbit, and goat. However, in many cases, suitable primary antibodies raised in different species are unavailable
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GNLY Rabbit pAb, Biotin conjugated(bs-2577R-Bio)-100ul
￥2980
