PGGT1B Rabbit pAb, AP conjugated(bs-9372R-AP)-100ul

PGGT1B Rabbit pAb, AP conjugat

ed(bs-9372R-AP)-100ul
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  • ¥2980
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  • bs-9372R-AP
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-9372R-AP
    英文名称PGGT1B Rabbit pAb, AP conjugated
    中文名称AP标记的香叶烯基转移酶1β抗体
    英文别名PGGT1B; GGTase-I beta; GGTase-1 beta; BGGI; Geranylgeranyl transferase type I subunit beta; Geranylgeranyl transferase type-1 subunit beta; GGTase-I-beta; GGTI; PGGT1B; PGTB1_HUMAN; Type I protein geranyl-geranyltransferase subunit beta;
    中文别名PGGT1β; GGTase-1 β; GGTase-I β.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human PGGT1 beta
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cell Biology > Other Antibodies > Other Antibodies

    亚基Heterodimer of an alpha and a beta subunit.
    相似性Belongs to the protein prenyltransferase subunit beta family.
    Contains 4 PFTB repeats. _x000D_
    功能Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. Acts on the Rac1, Rac2, Rap1A and Rap1B proteins. The beta subunit is responsible for peptide-binding.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994 [PubMed 8106351]). The enzyme is composed of a 48-kD alpha subunit (FNTA; MIM 134635) and a 43-kD beta subunit, encoded by the PGGT1B gene. The FNTA gene encodes the alpha subunit for both GGTase-I and the related enzyme farnesyltransferase.[supplied by OMIM, Mar 2010]

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

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