IL17F Rabbit pAb, AP conjugated(bs-2614R-AP)-100ul

IL17F Rabbit pAb, AP conjugate

d(bs-2614R-AP)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-2614R-AP
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-2614R-AP
    英文名称IL17F Rabbit pAb, AP conjugated
    中文名称AP标记的白介素-17F抗体
    英文别名Interleukin 17F; Cytokine ML-1; IL-17F; IL17F_HUMAN; Interleukin-17F; CANDF6; ML1.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human IL-17F
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Invasion/microenvironment > Angiogenesis > Angiogenic inhibitory factors

    Cardiovascular > Angiogenesis > Cytokines > Interleukin

    Cardiovascular > Angiogenesis > Inhibitors

    Immunology > Innate Immunity > Cytokines > Interleukins

    亚基Homodimer; disulfide-linked.
    亚细胞定位Secreted.
    组织特异性Expressed in activated, but not resting, CD4+ T-cells and activated monocytes.
    相似性Belongs to the IL-17 family.
    功能Stimulates the production of other cytokines such as IL-6, IL-8 and granulocyte colony-stimulating factor, and can regulate cartilage matrix turnover. Stimulates PBMC and T-cell proliferation. Inhibits angiogenesis.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料IL-17F is a member of IL-17 family of structurallyrelated cytokines that share a highly conserved C-terminal region, but differ from one another in their N-terminal regions and in their distinct biological roles. IL-17F is a homodimer of two 133 amino acid chains that are secreted by activated CD4+ Tcells and activated monocytes. The biological activities mediated by IL-17F are similar to those of IL-17. IL-17F stimulates the production of other cytokines such as IL-6, IL-8 and granulocyte colony stimulating factor. It can also regulate cartilage matrix turnover, stimulate PBMC and T cell proliferation, and inhibit angiogenesis. This recombinant human IL-17F is produced by human cells. Biological activity: The activity was measured by its ability to induce IL-6 expression in the NHDF adult fibroblasts. Reconstitution: Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

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