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100ul
| 产品编号 | bs-21534R-AP |
| 英文名称 | HATH6/Protein atonal homolog 8 Rabbit pAb, AP conjugated |
| 中文名称 | AP标记的螺旋环螺旋转录因子HATH6抗体 |
| 英文别名 | HATH6; 4933425C05Rik; HATH-6; HATH 6; ATOH8; ATOH8_HUMAN; Atonal homolog 6; atonal homolog 8(Drosophila); Atonal homolog 8; Basic helix loop helix transcription factor 6; bHLHa21; Class A basic helix-loop-helix protein 21; FLJ14708; FLJ38730; hATH6; Helix loop helix protein mATH-6; Helix-loop-helix protein hATH-6; Math6; Okadin; Protein atonal homolog 8; RGD1561512. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from mouse HATH6/Protein atonal homolog 8 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Developmental Biology > Organogenesis > Nervous system development Epigenetics and Nuclear Signaling > Transcription > Domain Families > HLH / Leucine Zipper > HLH Epigenetics and Nuclear Signaling > Transcription > Transcription Factors Neuroscience > Neurology process > Neurogenesis |
| 亚基 | Efficient DNA binding requires dimerization with another bHLH protein |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Expressed in lung, liver, kidney, heart and pancreas. Expressed in endothel of umbilical vessels. |
| 相似性 | Contains 1 basic helix-loop-helix (bHLH) domain. |
| 功能 | Putative transcription factor. May be implicated in specification and differentiation of neuronal cell lineages in the brain. May participate in kidney development and may be involved in podocyte differentiation |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Putative transcription factor. May be implicated in specification and differentiation of neuronal cell lineages in the brain. May participate in kidney development and may be involved in podocyte differentiation. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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文献和实验Incubating the membrane with primary antibody, which binds to the protein of interest Washing to remove any unbound primary antibody Incubating the membrane with a conjugated secondary antibody, which binds the first antibody Washing
Studies of the Ubiquitin Proteasome System
Triton X‐100 lysis buffer (see recipe ), ice cold Specific antibody to the protein of interest and matched control antibody, e.g., irrelevant antibody or serum from unimmunized rabbits
-4445 [40] Hockenbery D, Nunez G, Milliman C,Korsmeyer RDSSJ.Bcl-2 is an inne rmitoch ondrial membrane protein that programmed cell death.Nature,1990;348:334-336 [41] Mandal M, Wu X, Kumar R. Bcl-2 deregulation leads to inhibition of so dium butyrate
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