ITPR2 Rabbit pAb, HRP conjugated(bs-4243R-HRP)-100ul

ITPR2 Rabbit pAb, HRP conjugat

ed(bs-4243R-HRP)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-4243R-HRP
  • 2025年12月03日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-4243R-HRP
    英文名称ITPR2 Rabbit pAb, HRP conjugated
    中文名称HRP标记的5-三磷酸肌醇受体2抗体
    英文别名4; 5-trisphosphate receptor; Inositol 1 4 5 trisphosphate receptor type 2; Inositol 1, 4, 5-trisphosphate receptor type 2; Inositol 145 trisphosphate receptor type 2; InsP3 R2; InsP3R2; IP3 R2; IP3 receptor isoform 2; IP3R 2; IP3R2; ITPR 2; Itpr2; ITPR2_HUMAN; Type 2 inositol 1 4 5 trisphosphate receptor; Type 2 inositol 1; Type 2 inositol 145 trisphosphate receptor; Type 2 InsP3 receptor.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human ITPR2
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Cancer Metabolism > Response to hypoxia

    Metabolism > Pathways and Processes > Metabolism processes > Hypoxia

    Metabolism > Types of disease > Cancer

    Signal Transduction > Signaling Pathway > Calcium Signaling

    亚基Homotetramer. Interacts with CABP1.
    亚细胞定位Endoplasmic reticulum membrane; Multi-pass membrane protein.
    组织特异性Isoform Short is found in skeletal muscle and heart.
    翻译后修饰Phosphorylation by cAMP-dependent PKA on Ser-937 increases calcium release.
    相似性Belongs to the InsP3 receptor family._x000D_
    Contains 5 MIR domains.
    功能Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. This release is regulated by cAMP both dependently and independently of PKA (By similarity).
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}

     

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