Corin Rabbit pAb, PerCP-Cy5.5 conjugated(bs-7685R-PerCP-Cy5.5)-100ul

Corin Rabbit pAb, PerCP-Cy5.5

conjugated(bs-7685R-PerCP-Cy5.5)-100ul
收藏
  • ￥2980
  • Bioss已认证
  • bs-7685R-PerCP-Cy5.5
  • 2025年11月16日
  • 产品信息以Bioss网站为准
avatar
北京博奥森生物技术有限公司
品牌商
9 年钻石会员

  • 企业认证

    点击 QQ 联系

    • 相关产品推荐更多 >

    万千商家帮你免费找货

    0 人在求购买到急需产品
    • 详细信息
    • 技术资料
    • 应用范围：

      产品信息以Bioss网站为准

    • 规格：

      100ul

    产品编号bs-7685R-PerCP-Cy5.5
    英文名称Corin Rabbit pAb, PerCP-Cy5.5 conjugated
    中文名称PerCP-Cy5.5标记的心脏特异性丝氨酸蛋白酶抗体
    英文别名ATC 2; ATC2; Atrial natriuteric peptide converting enzyme; Corin serine peptidase; CRN; Heart specific serine proteinase; Heart specific serine proteinase ATC2; Lrp 4; Lrp4; Pro ANP convertase; Pro ANP converting enzyme; TMPRSS 10; Transmembrane protease serine 10.
    产品应用Flow-Cyt=1ug/Test

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human Corin
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA and 0.02% Proclin300.
    研究领域

    Cardiovascular > Blood > Blood Pressure regulation

    Cell Biology > Proteolysis / Ubiquitin > Proteolytic enzymes > Serine protease > TMPRSS

    亚细胞定位Cell membrane; Single-pass type II membrane protein. Isoform 2: Cell membrane; Single-pass type II membrane protein. Note=Less efficiently targeted to the cell membrane compared to isoform 1. Atrial natriuretic peptide-converting enzyme, 180 kDa soluble fragment: Secreted. Note=Soluble form produced following cleavage by ADAM10. Atrial natriuretic peptide-converting enzyme, 160 kDa soluble fragment: Secreted. Note=Soluble form produced following autocatalytic cleavage. Atrial natriuretic peptide-converting enzyme, 100 kDa soluble fragment: Secreted. Note=Soluble form produced following autocatalytic cleavage.
    组织特异性Highly expressed in heart. Expressed in heart myocytes. Also expressed in pregnant uterus.
    翻译后修饰N-glycosylated; required for processing and activation.
    相似性Belongs to the peptidase S1 family.
    Contains 2 FZ (frizzled) domains.
    Contains 7 LDL-receptor class A domains.
    Contains 1 peptidase S1 domain.
    Contains 1 SRCR domain.
    功能Serine-type endopeptidase involved in atrial natriuretic peptide hormone (N‌‌PPA) processing. Converts through proteolytic cleavage the non-functional propeptide N‌‌PPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-N‌‌PPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-N‌‌PPB the B-type natriuretic peptide.
    Isoform 2: has weaker endopeptidase activity compared to isoform 1._x000D_
    保存条件Store at 2-8°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Corin was first described as a trypsin-like serine proteinase in the heart which processed pro-atrial natriuretic peptide into the active form ANP. Corin cleaves pro-ANP at Arg98/Ser-99, and blocking Corin message inhibits pro-ANP processing. Null mutant mice lacking Corin develop hypertension, and a series of missense mutations have been identified in humans with high blood pressure and hypertension. Corin is a member of the type-II transmembrane serine proteinases, such as Hepsin, Epitheliasin, Matriptase and enteropeptidase. The Corin domain structure includes a cytoplasmic domain, a transmembrane domain, a spacer region, a frizzled-like domain, 5 LDL Receptor-like domains, another frizzled-like domain, 3 more LDLR-like repeats, a SRCR (Scavenger Receptor-Cysteine Rich) domain (also called macrophage scavenger-like domain), and finally the trypsin-like serine proteinase domain. The complex domain structure puts Corin into the “mosaic” TMPRSS family, so named because of the wide variety of domains.

     

    应用推荐稀释比例
    {Flow-Cyt}{1ug/Test}

     

    风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标技术资料

    暂无技术资料 索取技术资料

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    PerCP-Cy5.5 Tandem/PerCP-Cy5.5 Tandem/PerCP-Cy5.5 Tandem
    询价
    艾美捷科技有限公司
    2025年07月07日询价
    Integrin alpha 4 antibody [R1-2] (PerCP-Cy5.5)
    ￥5800
    深圳欣博盛生物科技有限公司
    2025年07月10日询价
    Integrin alpha 4 antibody [R1-2] (PerCP-Cy5.5)
    ￥5800
    GeneTex
    2025年07月09日询价
    Anti- CD4 Antibody (Clone Edu-2) PerCP-Cy5.5 Conjugated
    ￥3000
    上海联迈生物工程有限公司
    2025年07月12日询价
    PerCP-Cy5.5 小鼠 IgG1, 抗体
    ￥2060
    杭州斯达特生物科技有限公司
    2025年12月11日询价
    Corin Rabbit pAb, PerCP-Cy5.5 conjugated(bs-7685R-PerCP-Cy5.5)-100ul
    ￥2980