MTNR1A Rabbit pAb, AP conjugated(bs-0027R-AP)-100ul

MTNR1A Rabbit pAb, AP conjugat

ed(bs-0027R-AP)-100ul
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  • ¥2980
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  • bs-0027R-AP
  • 2025年11月13日
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      100ul

    产品编号bs-0027R-AP
    英文名称MTNR1A Rabbit pAb, AP conjugated
    中文名称AP标记的褪黑素受体1A/松果体素受体1A抗体
    英文别名MTR1A_HUMAN; Melatonin receptor type 1A; Melatonin Receptor 1A; Mel-1A-R; Mel1a receptor; MT1; MT 1; Mel 1A R;
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from the midlle of human MTNR1A
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Neuroscience > Endocrine system > Hypothalamic pituitary adrenal axis

    Neuroscience > Neurology process > Metabolism

    Neuroscience > Neurotransmission > Receptors / Channels > GPCR > More GPCR

    亚细胞定位Cell membrane; Multi-pass membrane protein.
    组织特异性Expressed in hypophyseal pars tuberalis and hypothalamic suprachiasmatic nuclei (SCN). Hippocampus.
    相似性Belongs to the G-protein coupled receptor 1 family.
    功能High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin. [provided by RefSeq, Jul 2008]

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

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