- ￥500 - 1230
- Elabscience
- 湖北武汉
- E-AB-F1202A
- 2025年09月28日
- WB;IHC-p
- Rabbit
- Human;Mouse;Rat
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- 详细信息
- 文献和实验
- 技术资料
- 形态：
液体
- 保存条件：
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
- 适应物种：
Human;Mouse;Rat
- 保质期：
12个月
- 库存：
999
- 宿主：
Rabbit
- 应用范围：
WB;IHC-p
- 抗体英文名：
Purified Anti-Human IL-21 Antibody[3A3-N2]
- 规格：
100μg/25μg
| 规格： | 100μg | 产品价格： | ￥1230.0 |
|---|---|---|---|
| 规格： | 25μg | 产品价格： | ￥500.0 |
Purified Anti-Human IL-21 Antibody[3A3-N2]
| Alternate Names |
CVID, Interleukin, IL21, CVID11, IL-21, Za11, Interleukin-21
|
| Cellular Localization |
Secreted
|
| Clone No | |
| Isotype |
Mouse IgG1,κ
|
| Leadtime |
咨询
|
| Verified Samples | Verified Samples in FCM: HEK293T cells transfected with pcDNA3.1 plasmid encoding Human IL-21 gene |
| Dilution |
FCM 2 μg/mL(0.5×106-1×106 cells)
|
| Background |
Interleukin-21 (IL-21) is the most recently described cytokine belonging to the common cytokine receptor gamma-chain family. Like other common gamma chain family members, IL-21 is a four alpha-helix bundle type I cytokine. It signals through a receptor complex consisting of IL-21 R and common gamma-chain/IL-2 R gamma. IL-21 is produced primarily by CD4+ T cells and natural killer T (NKT) cells and has a broad range of effects on a number of different cell types. IL-21 signaling in CD4+ T cells is required for both Th17 differentiation and the geneRation of T follicular helper (Tfh) cells, which support B cell differentiation and antibody production in germinal centers. IL-21 also directly regulates B cell prolifeRation and apoptosis in a context-dependent manner and can promote immunoglobulin production and isotype class switching. In addition, IL-21 signaling enhances the cytotoxicity of CD8+ T cells, natural killer cells, and NKT cells.
|
| Immunogen | Recombinant Human IL-21 protein |
| Abbre |
IL-21
|
| Swissprot |
Q9HBE4
|
| Host |
Mouse
|
| Reactivity |
Human
|
| Clonality |
Monoclonal
|
| Purification Method |
>98%, Protein A/G purified
|
| Applications | |
| Concentration |
≥ 1 mg/mL
|
| Conjugation |
Unconjugated
|
| Storage Buffer |
PBS, pH 7.2. Contains 0.05% proclin 300.
|
| Storage |
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
|
| Expiration Date |
12个月
|
| Shipping |
Ice bag
|
Purified Anti-Human IL-21 Antibody[3A3-N2]Elabscience®流式抗体致力于为您的流式细胞分析实验带来更优质的体验，已有3,000+指标，选用经典克隆株纯化抗体，产品涵盖抗人/大鼠/小鼠等，指标丰富。
Purified Anti-Human IL-21 Antibody[3A3-N2]Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Purified Anti-Human IL-21 Antibody[3A3-N2]产品更多产品信息查看欢迎咨询我们和搜索武汉伊莱瑞特Elabscience官网查看。
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文献和实验Culture and Proliferation of Highly Purified Adult Schwann Cells from Rat, Dog, and Man
This chapter presents fast and easy protocols to obtain highly purified cultures of proliferating adult rat, canine, and human Schwann cells. Cell preparation from predegenerated adult sciatic nerves combined with the use of melanocyte growth
Dual-Color ELISPOT Assay for the Simultaneous Detection of IL-2 and/or IFN- Secreting T Cells
with one of the positive control stimuli, i.e., CEF or anti-CD3 mAb (Step 13). Wells coated with anti-IL-2 coating buffer should contain only blue spots. Wells coated with anti-IFN- coating buffer should contain only red spots. i. Set sensitivity
Detection of Class Switching and IgE Synthesis in Human B Cells
events leading to IgE synthesis. This chapter will illustrate how human B cells (na�ve or memory) can be purified, stored, and cultivated in medium that is permissive for IgE synthesis and stimulated with IL-4 or IL-13 and CD40 activation
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