PE/Cyanine5 Anti-Human CD72 An

Lyb-2, Ly-19.2, Ly-32.2, CD72抗体, 人CD72, 人CD72流式抗体, AN00325

Membrane

3F3

Mouse IgG2b, κ

咨询

CD72 is a 39-43 kD type II membrane glycoprotein. It is a disulfide-linked homodimer belonging to C-type lectin family. CD72 is a pan-B cell marker expressed on pre-pre-B cells throughout B cell differentiation with the exception of plasma cells. It is also expressed on follicular dendritic cells, splenic red pulp macrophages (but not on peripheral blood monocytes), and liver Kupffer cells. CD72, a negative coreceptor of B cells, contains immunoreceptor tyrosine-based inhibitory motifs in the cytoplasmic domain which has been shown to recruit the tyrosine phosphatase SHP-1. Ligation of CD72 with its ligand regulates CD72 tyrosine dephosphorylation and SHP-1 dissociation to promote B cell activation and proliferation. CD100 and CD5 have been shown to be CD72 ligands. The CD100-CD72 interaction plays a role in maintenance of B cell homeostasis.

CD72

P21854

Mouse

Human

Monoclonal

PE/Cyanine5 Mouse IgG2b, κ Isotype Control[MPC-11]

FCM

Liquid

5 μL/Test

PE/Cyanine 5

PE/Cyanine5 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 670 nm (e.g., a 690/50 nm bandpass filter).

Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide.

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

12个月

冰袋

971