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- 技术资料
- 规格:
500ug
| 产品编号 | bs-8269P |
| 英文名称 | GIMAP3 Antibody Blocking Peptide |
| 中文名称 | GTP酶IMAP家族成员3封闭多肽 |
| 英文别名 | GTPase, IMAP family member 3 pseudogene; Ian4; Gimap5; 2010110D23Rik; GIMAP 3; GIMAP3; GTPase IMAP family member 3; GTPase of the immune associated protein 3; Immune associated nucleotide 4; Immunity associated nucleotide 4 protein. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Mitochondrion outer membrane; Single-pass type IV membrane protein. |
| 组织特异性 | May be restricted to certain hematopoietic cells. |
| 相似性 | Belongs to the IAN GTP-binding protein family. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | GIMAP3p is a murine mitochondrial membrane protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. The IAN/GIMAP family consists of GTP-binding proteins that share a unique primary structure and whose expression is finely regulated by T-cell receptor signals. Recent studies have shown that IAN/GIMAP family proteins crucially regulate the survival of T cells during development, selection and homeostasis, and are possibly linked to the onset of T-lymphopenia, leukemia and autoimmunity. IAN/GIMAP family proteins might also take part in mitochondrial regulation of lymphocyte apoptosis by interacting with Bcl-2 family proteins. The human GIMAP (GTPase of the immunity-associated protein) gene family includes seven functional members residing on (human) chromosome 7q36.1 and one pseudogene (hGIMAP3). |
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